(S) -Ro 32-0432

CAT: 0931-T84742-01Size: 10 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0931-T84742-01Size:10 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

CAS Number

1781828-85-0

Target

Others, PKC

Related Pathways

Others, Chromatin/Epigenetic, Cytoskeletal Signaling

Bioactivity

(S) -Ro 32-0432 is a potent, selective inhibitor of protein kinase C (PKC) and G protein-coupled receptor kinase 5 (GRK5), demonstrating ATP-competitive and oral activity. It presents IC50 values of 9.3 nM for PKCα, 28 nM for PKCβI, 30 nM for PKCβII, 36.5 nM for PKCγ, and 108.3 nM for PKCε, showcasing its effectiveness against multiple PKC isoforms. Additionally, (S) -Ro 32-0432 inhibits T-cell activation, indicating its potential application in the research of chronic inflammatory and autoimmune diseases [1] [2].

Smiles

O=C1C(C2=C3N(C=4C2=CC=CC4)CC[C@H](CN(C)C)C3)=C(C(=O)N1)C=5C=6C(N(C)C5)=CC=CC6.Cl

Molecular Formula

C28H29ClN4O2

Molecular Weight

489.01

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Related Products

Catalog	Name
T23244-01	Ro 32-0432 hydrochloride
T26105-01	Ro 32-7315
T16769-01	Ro 363
T68134-01	Ro-3201195
T6971-01	Ro 5126766
T3915-01	Ginsenoside Ro
T5513-01	RO-3
T9901A-1799-01	RO-5429083
T87339-01	RO-275
T16794-01	RO 4938581

Alternative Products

Catalog	Name
sc-3549A	Ro-32-0432
B6798-1	Ro 32-0432 hydrochloride
HY-108601A	(S) -Ro 32-0432
HY-108601	(S) -Ro 32-0432 (free base)
bs-75398C-01	Bisindolylmaleimide XI . hydrochloride [Ro 32-0432]
MBS6071218-01	Bisindolylmaleimide XI hydrochloride (Ro 32-0432, BIM XI)
GK0415-1mg	Ro 31-0432
144382	Connexin 32 (Connexin-32)
sc-59948	Connexin 32 (CXN-32)
B2702-07	Brain Natriuretic Peptide 32 (BNP-32) (10-32) (rat) (BNP-32)

(S) -Ro 32-0432

Related Products

Alternative Products

Popular Products