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SB 203580 sulfone

CAT: 0931-T84519-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T84519-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
152121-46-5
Target
Others, p38 MAPK
Related Pathways
Others, MAPK
Bioactivity
SB 203580 sulfone, an analog of the p38 MAP kinase inhibitor SB 203580, inhibits IL-1 production in monocytes and binds competitively with CSAID binding proteins (CSBP), inhibiting stress response signaling. It exhibits an IC50 of 0.2 μM for IL-1 inhibition and 0.03 μM for CSBP-mediated signaling inhibition [1].
Smiles
FC1=CC=C(C2=C(N=C(N2)C3=CC=C(S(C)(=O)=O)C=C3)C=4C=CN=CC4)C=C1
Molecular Formula
C21H16FN3O2S
Molecular Weight
393.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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