SB 699551

CAT: 0931-T23325L-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T23325L-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
791789-61-2
Target
Akt|||5-HT Receptor|||FOXO
Related Pathways
Apoptosis|||PI3K/Akt/mTOR signaling|||Neuroscience|||GPCR/G Protein|||Cytoskeletal Signaling
Purity
0.9983
Bioactivity
SB 699551 is a selective 5-HT5A antagonist (Ki=6.31 nM) that enhances 5-HT neuronal function. It inhibits SERT (Ki=25.12 nM), reduces phosphorylation levels of AKT and FOXO1, and exhibits inhibitory effects against breast cancer.
Smiles
O=C(N(CC=1C=CC(=CC1)C2=CC=C(C=C2)CNCCC=3C=CC=CC3)CCN(C)C)CCC4CCCC4
Molecular Formula
C34H45N3O
Molecular Weight
511.74
Shipping Conditions
Cool pack
Storage Temperature
-20°C