MAGLi 432

• Target:

  Others|||MAGL

• Related Pathways:

  Metabolism|||Others

• Bioactivity:

  MAGLi 432 is a potent, highly selective, non-covalent, reversible (MAGL) inhibitor that binds with high affinity to the MAGL active site, with IC50 values of 4.2 nM (human enzyme) and 3.1 nM (mouse enzyme), MAGLi 432 can be used to study neurological disorders such as chronic inflammation, multiple sclerosis, blood-brain barrier dysfunction, Alzheimer's disease and Parkinson's disease.

• Smiles:

  C(=O)(N1C[C@@]2(N(C[C@H](CC2)C3=CC=C(Cl)C=C3)CC1)[H])C4=C(Br)C(OC)=CC=C4

• Molecular Formula:

  C22H24BrClN2O2

• Molecular Weight:

  463.8

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2361575-20-2