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Tiger17 TFA

CAT: 0931-T83744-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T83744-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Bioactivity
Tiger17, a cyclic peptide derivative of tigerinin-RC1 and tigerinin-RC2—antimicrobial peptides from the crab-eating frog (F. cancrivora) skin secretions—enhances HaCaT keratinocytes and human skin fibroblasts proliferation at 5 to 20 μg/ml concentrations, and promotes HaCaT cell migration at 20 μg/ml. Additionally, Tiger17 augments RAW 264.7 macrophages' recruitment and secretion of TGF-β1 and IL-6. When topically applied at 20 μg/ml, it accelerates wound closure and re-epithelialization in a mouse model of full-thickness dermal wounds.
Smiles
O=C(N[C@H](C(N1[C@](CCC1)([H])C(N[C@H](C(N2[C@](CCC2)([H])C(N[C@H](C(N3[C@](CCC3)([H])C(N[C@H](C(N[C@@H](CSSC4)C(N[C@H](C(N)=O)CC5=CN=CN5)=O)=O)CCCNC(N)=N)=O)=O)CCCCN)=O)=O)CCCCN)=O)=O)CCCCN)[C@H]4NC([C@@H](N)CC6=CNC7=CC=CC=C67)=O.OC(C(F)(F)F)=O
Molecular Formula
C62H97N21O11S2.XCF3COOH
Molecular Weight
1376.7
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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