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PapRIV TFA

CAT: 0931-T83734-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T83734-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Bioactivity
PapRIV, a quorum-sensing heptapeptide derived from B. cereus, undergoes synthesis as a 48-amino acid polypeptide. This compound is secreted and then extracellularly processed by NprB proteases into its active form. At concentrations ranging from 1-25 μM, PapRIV triggers the production of IL-6 and TNF-α, as well as NF-κB translocation, specifically in BV-2 microglia cells.
Smiles
O=C([C@@H](N)CO)N[C@H](C(N[C@@H](CC(C)C)C(N1CCC[C@H]1C(N[C@@H](CC2=CC=CC=C2)C(N[C@H](C(N[C@H](C(O)=O)CC3=CNC=N3)=O)CCC(O)=O)=O)=O)=O)=O)CC(O)=O.OC(C(F)(F)F)=O
Molecular Formula
C38H53N9O13.XCF3COOH
Molecular Weight
843.9
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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