Products for Research Use Only
RegisterLogin

D359-0396

CAT: 0931-T82621-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T82621-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
1031977-31-7
Target
Pyroptosis, NOD-like Receptor (NLR)
Related Pathways
Apoptosis, Immunology/Inflammation
Bioactivity
D359-0396, an orally active NLRP3 inflammasome inhibitor, mitigates pyroptosis and reduces IL-1β release in macrophages by inhibiting the oligomerization of NLRP3, ASC, and the cleavage of GSDMD. The compound is effective in alleviating Experimental Autoimmune Encephalomyelitis (EAE) and enhances survival following septic shock in mice [1].
Smiles
O=C1C2=CN3C=4C=CC=CC4NC(C5=CC=C(C=C5)C(C)C)C3=C2N(C(=O)N1C)C
Molecular Formula
C24H24N4O2
Molecular Weight
400.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
T12238-01NNC 55-0396
T201932-01DSP-0390
T87647-01XRD-0394
T29108-01VL-0395
T127530-01Compound STOCK1N-03926
T127529-01Compound STOCK1N-03962
T69765-01NPD-039
T8972-01FIT-039
T63165-01LX-039
T10799-01CHMFL-ABL-039

Alternative Products

CatalogName
GTR19218024-01D359-0396
MBS3840909-01NNC 55-0396
A15188-100NNC 55-0396 100mg
A15188-1NNC 55-0396 1mg
GTR19269052-01(Rac) -NNC 55-0396
526807NNC 55-0396 HCl
A15188-5NNC 55-0396 5mg
256008NNC 55-0396 dihydrochloride
A15188-10NNC 55-0396 10mg
A15188-50NNC 55-0396 50mg

Popular Products