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DSP-0390

CAT: 0931-T201932-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T201932-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2376765-57-8
Bioactivity
DSP-0390 is an oral inhibitor of emopamil binding protein (EBP) . It effectively suppresses the EBP enzyme, which is involved in a critical late-stage step of cholesterol biosynthesis. By inhibiting the synthesis of new cholesterol, DSP-0390 selectively induces cytotoxicity in rapidly proliferating GBM cells. In human GBM xenograft models, DSP-0390 has demonstrated significant antitumor activity.
Smiles
CC1(C)[C@@]2(CC3(CO[C@]2(C=4C(O1)=CC(Cl)=CC4)[H])CCN(CCN5C=CN=C5)CC3)[H]
Molecular Formula
C23H30ClN3O2
Molecular Weight
415.96
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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