LX-039

• Target:

  Estrogen Receptor/ERR|||Others

• Related Pathways:

  Endocrinology/Hormones|||Others

• Bioactivity:

  LX-039 is a potent, selective, orally active estrogen receptor degrader (EC50: 2.99 nM) with antitumor effects.LX-039 has indole C-3 chloride atoms.LX-039 has good pharmacokinetic properties in mice, low clearance, high blood levels and oral exposure.

• Smiles:

  C(=C(CC)C1=C(Cl)C=C(F)C=C1)(C2=C(Cl)C=3C(N2)=CC=CC3)C4=CC=C(C=CC(O)=O)C=C4

• Molecular Formula:

  C27H20Cl2FNO2

• Molecular Weight:

  480.36

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2135341-09-0