LX-039

• Target :

  Estrogen Receptor/ERR|||Others

• Related Pathways :

  Endocrinology/Hormones|||Others

• Bioactivity :

  LX-039 is a potent, selective, orally active estrogen receptor degrader (EC50: 2.99 nM) with antitumor effects.LX-039 has indole C-3 chloride atoms.LX-039 has good pharmacokinetic properties in mice, low clearance, high blood levels and oral exposure.

• Smiles :

  C(=C(CC)C1=C(Cl)C=C(F)C=C1)(C2=C(Cl)C=3C(N2)=CC=CC3)C4=CC=C(C=CC(O)=O)C=C4

• Molecular Formula :

  C27H20Cl2FNO2

• Molecular Weight :

  480.36

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2135341-09-0