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HTH-02-006

CAT: 0931-T82165-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T82165-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
AMPK
Related Pathways
PI3K/Akt/mTOR signaling, Chromatin/Epigenetic
Bioactivity
HTH-02-006, a NUAK2 inhibitor (IC50 = 126 nM), decreases phosphorylated MYPT1 levels in HuCCT-1 cells and inhibits YAP-driven cell proliferation, hepatomegaly, and tumorigenesis. Additionally, it possesses an antifibrotic protective effect [1] [2].
Smiles
IC1=CN=C(NC2=CC=C(N3CCN(C)CC3)C=C2OC)N=C1OC4=CC(NC(CC)=O)=CC=C4
Molecular Formula
C25H29IN6O3
Molecular Weight
588.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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