(S) -crizotinib

• Target:

  MTH1|||Apoptosis|||DNA/RNA Synthesis

• Related Pathways:

  DNA Damage/DNA Repair|||Cell Cycle/Checkpoint|||Apoptosis

• Purity:

  0.9989

• Bioactivity:

  (S) -crizotinib (ent-crizotinib) ?IC50 of 72 nM?, an effective MTH1 (NUDT1) inhibitor, is the (S) -enantiomer of crizotinib.

• Smiles:

  C[C@H](Oc1cc(cnc1N)-c1cnn(c1)C1CCNCC1)c1c(Cl)ccc(F)c1Cl

• Molecular Formula:

  C21H22Cl2FN5O

• Molecular Weight:

  450.34

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1374356-45-2