Crizotinib-d5

• Target:

  ROS Kinase|||Autophagy|||c-Met/HGFR|||ALK

• Related Pathways:

  Angiogenesis|||Tyrosine Kinase/Adaptors|||Autophagy

• Bioactivity:

  Crizotinib-d5 is a deuterated compound of Crizotinib. Crizotinib has a CAS number of 877399-52-5. Crizotinib is an ATP-competitive small-molecule tyrosine kinases inhibitor of c-MET (IC50: 8 nM) and ALK (IC50: 20 nM) receptor.

• Smiles:

  C1(F)C(Cl)=C([C@H](OC2C=C(C3C=NN(C4([2H])C([2H])([2H])CNCC4([2H])[2H])C=3)C=NC=2N)C)C(Cl)=CC=1

• Molecular Formula:

  C21H17D5Cl2FN5O

• Molecular Weight:

  455.37

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1395950-84-1