PARG-IN-4

• Target:

  Apoptosis|||Poly (ADP-ribose) Glycohydrolase (PARG)

• Related Pathways:

  Apoptosis|||Cell Cycle/Checkpoint

• Purity:

  0.9851

• Bioactivity:

  PARG-IN-4 (compound A) is an orally active and cell-membrane permeable PARG inhibitor (EC50=1.9 nM) that inhibits tumour growth in mice with antitumour activity.

• Smiles:

  S(NC1(C)CC1)(=O)(=O)C=2C=C3C(=C(C2)N4C[C@H](C)N[C@@H](C)C4)C=NN3C=5SC(C(F)F)=NN5

• Molecular Formula:

  C20H25F2N7O2S2

• Molecular Weight:

  497.59

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2988890-20-4