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PAR4 antagonist 4

CAT: 0931-T209709-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T209709-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3057206-41-1
Target
Protease-activated Receptor
Related Pathways
GPCR/G Protein
Bioactivity
PAR4 antagonist4 (Compound 37) is a selective antagonist of protease-activated receptor 4 (PAR4) . It exhibits antiplatelet activity with an IC50 of 14.2 nM. Moreover, PAR4 antagonist3 enhances metabolic stability in human liver microsomes, showing a half-life (T1/2) of 42.5 minutes.
Smiles
FC1=CC=C(OCC2OC=3C=CC=4C=C(OC4C3OC2)C=5N=C6SC(=NN6C5)OC)C=C1
Molecular Formula
C22H16FN3O5S
Molecular Weight
453.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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