PARG-IN-7

• Target:

  Poly (ADP-ribose) Glycohydrolase (PARG)

• Related Pathways:

  Cell Cycle/Checkpoint

• Bioactivity:

  PARG-IN-7 (Example 38) is a Poly ADP-ribose glycohydrolase (PARG) inhibitor with an IC50 of less than 0.1 ?M. It reduces the viability of HCC1806-XRCC1 knockdown (KD) cells, exhibiting an IC50 of less than 1 ?M. PARG-IN-7 is applicable in cancer research.

• Smiles:

  N#CC1(NS(=O)(=O)C=2C=C3C(C=NN3C4=NN=C(S4)C(F)F)=C(C2)N5CCN(C(=O)C(C)C)CC5)CC1

• Molecular Formula:

  C22H24F2N8O3S2

• Molecular Weight:

  550.61

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2632343-19-0