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PROTAC EGFR degrader 7 diTFA

CAT: 0931-T81380-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T81380-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
PROTACs
Related Pathways
PROTAC
Bioactivity
PROTAC EGFR degrader 7 (compound 13b) is a potent, selective, CRBN-recruiting EGFRL858R/T790M degrader with a DC50 of 13.2 nM. It effectively inhibits NCI-H1975 cell proliferation with an IC50 of 46.82 nM, induces apoptosis, and causes G2/M phase arrest. This compound shows antitumor activity and is applicable in non-small cell lung cancer (NSCLC) research.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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