Products for Research Use Only

PROTAC EGFR degrader 2

CAT: 0931-T74333-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T74333-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
EGFR, PROTACs
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling, PROTAC
Bioactivity
PROTAC EGFR degrader 2 is a potent compound with an IC50 of 4.0 nM, demonstrating strong antiproliferative activity, and a DC50 of 36.51 nM, indicating robust EGFR degradation activity. It is suitable for synthesizing nitroreductase (NTR) -responsive PROTACs [1].
Molecular Formula
C58H72ClFN12O8S
Molecular Weight
1151.78
Shipping Conditions
Ice Packs
Storage Temperature
-20°C