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SEH/FLAP-IN-1

CAT: 0931-T81181-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T81181-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Epoxide Hydrolase, FLAP
Related Pathways
Metabolism, Immunology/Inflammation
Bioactivity
SEH/FLAP-IN-1 (Compound 46A) serves as a dual inhibitor targeting both sEH and FLAP, effectively suppressing 5-LOX product formation with an EC50 of 11 nM in SACM-stimulated PBMCs, inhibiting sEH activity (EC50: 18 nM), and reducing thromboxane production. This compound is utilized in the study of inflammatory diseases [1].
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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