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SWTX-143

CAT: 0931-T81056-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T81056-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2766575-48-6
Target
YAP
Related Pathways
Stem Cells
Bioactivity
SWTX-143, a novel covalent inhibitor, specifically and irreversibly binds to the palmitoylation pocket of all four TEAD isoforms, inhibiting the transcriptional activity of the YAP/TAZ-TEAD complex and demonstrating antitumor activity [1].
Smiles
O=C(C=C)NC1CC=2C(N)=CC=CC2N(C3=CC=C(C=C3)C(F)(F)F)C1
Molecular Formula
C19H18F3N3O
Molecular Weight
361.36
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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