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UTX-143

CAT: 0804-HY-163365-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-163365-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
UTX-143 is an inhibitor of Na+/H+ exchange protein (NHE5) . UTX-143 has antitumor activity[1].
UNSPSC
12352005
Target
Na+/H+ Exchanger (NHE)
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/utx-143.html
Solubility
10 mM in DMSO
Smiles
O=C(NC(N)=N)C(N=C1C2=CC=C(C)C=C2)=C(N=C1N(CCO)C)N
Molecular Formula
C16H21N7O2
Molecular Weight
343.38
References & Citations
[1]Shinohara Y, et al. Development of UTX-143, a selective sodium-hydrogen exchange subtype 5 inhibitor, using amiloride as a lead compound. Bioorg Med Chem. 2024 Feb 1;99:117603.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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