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Clofarabine-5'-triphosphate

CAT: 0931-T203136-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T203136-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
134646-41-6
Target
DNA/RNA Synthesis
Related Pathways
Cell Cycle/Checkpoint, DNA Damage/DNA Repair
Bioactivity
Clofarabine-5'-triphosphate is a metabolite of Clofarabine, produced via phosphorylation by deoxycytidine kinase (dCK) . It exhibits cytotoxicity in cancer cells by inhibiting DNA synthesis and DNA repair.
Smiles
F[C@@H]1[C@H](N2C=3C(N=C2)=C(N)N=C(Cl)N3)O[C@H](COP(OP(OP(=O)(O)O)(=O)O)(=O)O)[C@H]1O
Molecular Formula
C10H14ClFN5O12P3
Molecular Weight
543.62
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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