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ZZM-1220

CAT: 0931-T79776-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T79776-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Histone Methyltransferase, Apoptosis
Related Pathways
Chromatin/Epigenetic, Apoptosis
Bioactivity
ZZM-1220, a covalent inhibitor of histone lysine methyltransferase G9a/GLP, exhibits IC50 values of 458 nM for G9a and 924 nM for GLP. It effectively inhibits H3K9me2 in cells, induces apoptosis in triple-negative breast cancer (TNBC) cells, and arrests the cell cycle at the G2/M phase [1].
Molecular Formula
C25H29N5O3
Molecular Weight
447.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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