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Anti-inflammatory agent 56

CAT: 0931-T79670-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T79670-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2413127-32-7
Target
COX
Related Pathways
Immunology/Inflammation, Neuroscience
Bioactivity
Anti-inflammatory agent 56 (Compound 9), a selective COX-2 inhibitor with an IC50 of 0.54 μM, exhibits antioxidant and anti-inflammatory properties by inhibiting oxidative stress-induced cell death and neuroinflammation through the suppression of Keap1, COX-2, and iNOS. It demonstrates low acute toxicity in mice with an LD50 of 1000 mg/kg [1].
Smiles
OC1=C(C=2N(N=C(N2)C3=C(O)C=C(C(F)(F)F)C=C3)C4=CC=C(S(N)(=O)=O)C=C4)C=CC=C1
Molecular Formula
C21H15F3N4O4S
Molecular Weight
476.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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