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EGFR-IN-81

CAT: 0931-T79327-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T79327-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
EGFR
Related Pathways
JAK/STAT signaling, Tyrosine Kinase/Adaptors, Angiogenesis
Bioactivity
EGFR-IN-81 (Compound 10i), an EGFR inhibitor, demonstrates potent activity by inhibiting EGFR WT and the L858R/T790M mutation at IC50 values of 4.38 nM and 5.69 nM, respectively. It also exhibits cytotoxic effects against MCF-7 and HCT116 cell lines with IC50 values of 2.07 μM and 6.72 μM, respectively [1].
Molecular Formula
C28H24F3N5O4
Molecular Weight
551.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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