AChE-IN-81

• Target:

  Cholinesterase (ChE) |||Apoptosis

• Related Pathways:

  Apoptosis|||Neuroscience

• Bioactivity:

  AChE-IN-81 (compound 22) is a reversible, selective inhibitor of AChE with an 80.0% inhibition rate and an IC50 of 3.7 ?M. It binds to AChE with an affinity (Kd) of 5.37 ?M. AChE-IN-81 effectively reduces apoptosis in zebrafish brain cells and shows potential neuroprotective activity in an H2O2-induced SH-SY5Y cell damage model.

• Molecular Formula:

  C37H54ClNO5

• Molecular Weight:

  628.28

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C