MK-8768

• Target :

  Others|||GluR

• Related Pathways :

  Others|||Neuroscience

• Bioactivity :

  MK-8768 is a potent, selective, and orally bioavailable negative allosteric modulator of the mGluR2 class, exhibiting an IC50 of 9.6 nM and characterized by excellent brain permeability.

• Smiles :

  C(N)(=O)C=1C=C(C2=C(C=C(CN3C[C@H](C(F)(F)F)O[C@H](C)C3)C=C2)N1)C4=CN(C)N=C4

• Molecular Formula :

  C21H22F3N5O2

• Molecular Weight :

  433.43

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1432729-22-0