TRAP1-IN-1

• Target:

  Mitochondrial Metabolism|||Phosphatase|||HSP|||OXPHOS

• Related Pathways:

  Metabolism|||Cytoskeletal Signaling|||Apoptosis

• Bioactivity:

  TRAP1-IN-1 (compound 35) is a selective TRAP1 inhibitor that disrupts TRAP1 tetramer stability, induces degradation of TRAP1 downstream proteins, inhibits OXPHOS, and disrupts mitochondrial membrane potential.

• Smiles:

  O=C (C1=CC=C (O) C (=C1) C (=O) N2CC3=CC=C (OCCC[P+] (C=4C=CC=CC4) (C=5C=CC=CC5) C=6C=CC=CC6) C=C3C2) N7CC=8C=CC=C (F) C8C7.[F-][P+5] ([F-]) ([F-]) ([F-]) ([F-]) [F-]

• Molecular Formula:

  C45H39F7N2O4P2

• Molecular Weight:

  866.74

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3031102-94-7