Antitrypanosomal agent 14

• Target:

  Parasite|||GSK-3

• Related Pathways:

  PI3K/Akt/mTOR signaling|||Stem Cells|||Microbiology/Virology

• Bioactivity:

  Antitrypanosomal agent 14 (Compound 1), a potent T. brucei inhibitor with an effective concentration (EC50) of 0.47 ?M, also inhibits Tb GSK3 with an inhibitory concentration (IC50) of 12 ?M, and is utilized in the research of Human African Trypanosomiasis [1].

• Smiles:

  C(C(C)(C)C)(=O)C1=C(N)N=C(NC2CCCCC2)S1

• Molecular Formula:

  C14H23N3OS

• Molecular Weight:

  281.42

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1447933-37-0