Anticancer agent 127

• Target :

  IAP

• Related Pathways :

  Apoptosis

• Bioactivity :

  Anticancer agent 127 (142D6), an IAP inhibitor, covalently binds to the BIR3 domains of XIAP, cIAP1, and cIAP2, with IC50 values of 12 nM, 14 nM, and 9 nM, respectively, demonstrating anticancer effects [1].

• Smiles :

  N(C(=O)[C@H]1N(C([C@@H](NC([C@@H](NC)C)=O)[C@@H]2CCCCC2)=O)CCC1)[C@H]3C=4C(=C(OS(F)(=O)=O)C=CC4)CC3

• Molecular Formula :

  C26H37FN4O6S

• Molecular Weight :

  552.66

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2410953-19-2