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WM-586

CAT: 0931-T79120-01Size: 5 mgDry Ice: NoHazardous: No
T79120-015 mg
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AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2894832-05-2
Target
Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic
Bioactivity
WM-586 is a covalent inhibitor of WDR5 that impedes the WDR5-MYC binding. It selectively reduces the interaction between WDR5 and MYC with an IC50 value of 101 nM, as determined by the HTRF assay [1].
Smiles
FC1=C(C[C@@H](CCCC)C(=O)NC2=NN=NN2)C(F)=CC(C2C=CC=C(S(=O)(=O)F)C=2)=C1
Molecular Formula
C20H20F3N5O3S
Molecular Weight
467.47
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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