ACP-5862

CAT: 0931-T10240-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T10240-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2230757-47-6
Target
BTK|||Drug Metabolite|||Cytochromes P450
Related Pathways
Tyrosine Kinase/Adaptors|||Metabolism|||Angiogenesis
Bioactivity
ACP-5862 is a major active and pyrrolidine ring-opened metabolite of Acalabrutinib (IC50: 5.0 nM for BTK) . Acalabrutinib is an irreversible and highly selective BTK inhibitor (IC50: 3 nM; EC50: 8 nM) .
Smiles
CC#CC(=O)NCCCC(=O)c1nc(-c2ccc(cc2)C(=O)Nc2ccccn2)c2c(N)nccn12
Molecular Formula
C26H23N7O3
Molecular Weight
481.51
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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