Products for Research Use Only
RegisterLogin

CRBN ligand-586

CAT: 0013-GTR19275547-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19275547-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CRBN ligand-586 is a ligand for the E3 ubiquitin ligase cereblon (CRBN) and is used to recruit the cereblon protein. It can be linked via a linker to a target protein ligand to form a PROTAC.
CAS Number
2925085-03-4
Smiles
O=C1NC (=O) CCN1C2=CC=CC=3C (Br) =NN (C32) C
Molecular Formula
C12H11BrN4O2
Molecular Weight
323.15
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

1-(3-bromo-1-methyl-1H-indazol-7-yl)-1,3-diazinane-2,4-dione
CAS Number2925085-03-4
PubChem CID169548904
IUPAC Name1-(3-bromo-1-methylindazol-7-yl)-1,3-diazinane-2,4-dione
Molecular FormulaC12H11BrN4O2
Molecular Weight323.15
XLogP1.3
Topological Polar Surface Area67.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count1
Heavy Atom Count19
Formal Charge0
Complexity405
SMILES
CN1C2=C(C=CC=C2N3CCC(=O)NC3=O)C(=N1)Br
InChI
InChI=1S/C12H11BrN4O2/c1-16-10-7(11(13)15-16)3-2-4-8(10)17-6-5-9(18)14-12(17)19/h2-4H,5-6H2,1H3,(H,14,18,19)
InChIKey
QDXGHKUNDTZVGL-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 1-(3-bromo-1-methyl-1H-indazol-7-yl)-1,3-diazinane-2,4-dione
CAS: 2925085-03-4
CID: 169548904
Formula: C12H11BrN4O2
MW: 323.15
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight323.15
XLogP31.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count1
Exact Mass322.00654
Monoisotopic Mass322.00654
Topological Polar Surface Area67.2 Ų
Heavy Atom Count19
Formal Charge0
Complexity405
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19249891-01CRBN ligand-16
GTR19249567-01CRBN ligand-148
GTR19249350-01CRBN ligand-14
GTR19249319-01CRBN ligand-164
GTR19249205-01CRBN ligand-45
GTR19249056-01CRBN ligand-183
GTR19240334-01CRBN ligand-11
GTR19277390-01CRBN ligand-337
GTR19277346-01CRBN ligand-413
GTR19277146-01CRBN ligand-297

Alternative Products

CatalogName
HY-W953078CRBN ligand-586
HY-179733CRBN ligand-191
HY-169989-01CRBN ligand-11
HY-171224CRBN ligand-45
HY-170213CRBN ligand-183
HY-170108CRBN ligand-47
HY-170075CRBN ligand-16
T205631-01CRBN ligand-112
T205588-01CRBN ligand-110
HY-W999738CRBN ligand-834

Popular Products