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673-A

CAT: 0931-T71998-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T71998-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
109437-62-9
Target
Dehydrogenase, Necroptosis, Mitochondrial Metabolism, Others
Related Pathways
Apoptosis, Metabolism, Others
Bioactivity
673-A is an aldehyde dehydrogenase (ALDH1A) inhibitor that depletes CD133+ cancer stem cells (CSC) in ovarian cancer cell lines. 673-A triggers necroptosis in ovarian CSCs and induces expression of mitochondrial uncoupling proteins (UCP) . 673-A also overcomes chemotherapy resistance in vivo.
Smiles
O=CC1=CC=C(C=C1)N1CC2=CC=CC=C2C1
Molecular Formula
C15H13NO
Molecular Weight
223.27
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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