MY-1576

• Target :

  Hippo pathway|||FAK|||YAP

• Related Pathways :

  Stem Cells|||Angiogenesis|||Tyrosine Kinase/Adaptors|||Cytoskeletal Signaling

• Bioactivity :

  MY-1576 is a FAK inhibitor with an IC50 of 8 nM. It activates the Hippo pathway, thereby inhibiting YAP/TAZ regulation. Additionally, MY-1576 effectively suppresses tumor growth in the KYSE30 xenograft mouse model, demonstrates good safety, and efficiently downregulates FAK autophosphorylation and YAP/TAZ levels in vivo.

• Molecular Formula :

  C25H29ClN8O2

• Molecular Weight :

  509

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C