MY-1576

CAT: 0931-T205360-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T205360-01Size:10 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

Hippo pathway, FAK, YAP

Related Pathways

Stem Cells, Angiogenesis, Tyrosine Kinase/Adaptors, Cytoskeletal Signaling

Bioactivity

MY-1576 is a FAK inhibitor with an IC50 of 8 nM. It activates the Hippo pathway, thereby inhibiting YAP/TAZ regulation. Additionally, MY-1576 effectively suppresses tumor growth in the KYSE30 xenograft mouse model, demonstrates good safety, and efficiently downregulates FAK autophosphorylation and YAP/TAZ levels in vivo.

Molecular Formula

C25H29ClN8O2

Molecular Weight

509

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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