Anticancer agent 139

• Target :

  Microtubule Associated|||Others

• Related Pathways :

  Cytoskeletal Signaling|||Others

• Bioactivity :

  Compound 6h (Anticancer Agent 139) exhibits potent anticancer activity, engaging in a ?-cationic interaction with Lys352 of Tubulin and demonstrating high efficacy against SNB-19, OVCAR-8, and NCI-H460 with PGIs of 86.61, 85.26, and 75.99, respectively. Moreover, it shows moderate activity against a range of other cancer cell lines — HOP-62, SNB-75, ACHN, NCI/ADR-RES, 786-O, A549/ATCC, HCT-116, and MDA-MB-231 — with PGIs between 51.88 and 67.55 [1].

• Molecular Formula :

  C16H12F3N3O

• Molecular Weight :

  319.28

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C