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Anticancer agent 139

CAT: 0931-T78780-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T78780-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Microtubule Associated, Others
Related Pathways
Cytoskeletal Signaling, Others
Bioactivity
Compound 6h (Anticancer Agent 139) exhibits potent anticancer activity, engaging in a π-cationic interaction with Lys352 of Tubulin and demonstrating high efficacy against SNB-19, OVCAR-8, and NCI-H460 with PGIs of 86.61, 85.26, and 75.99, respectively. Moreover, it shows moderate activity against a range of other cancer cell lines — HOP-62, SNB-75, ACHN, NCI/ADR-RES, 786-O, A549/ATCC, HCT-116, and MDA-MB-231 — with PGIs between 51.88 and 67.55 [1].
Molecular Formula
C16H12F3N3O
Molecular Weight
319.28
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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