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Anticancer agent 136

CAT: 0931-T78764-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T78764-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Apoptosis
Related Pathways
Apoptosis
Bioactivity
Anticancer agent 136 (compound 22), a C17-triazole analogue of Geldanamycin (GDM), exhibits an IC50 value of 3.38 μM against human dermal fibroblasts (HDF) and binds to Heat shock protein 90 (Hsp90) with a dissociation constant (Kd) of 3.86 μM, demonstrating its apoptosis-inducing capabilities [1].
Molecular Formula
C40H50N6O8
Molecular Weight
742.86
Shipping Conditions
Ice Packs
Storage Temperature
-20°C