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Smurf1-IN-1

CAT: 0931-T78721-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T78721-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1824708-03-3
Target
E1/E2/E3 Enzyme
Related Pathways
Ubiquitination
Bioactivity
Smurf1-IN-1, a selective E3 ubiquitin protein ligase 1 (SMURF1) inhibitor, exhibits oral activity with an IC50 of 92 nM and demonstrates considerable efficacy in a rat model of pulmonary hypertension [1].
Smiles
O=C(C1=C(C)N(C2=CC=C(C3CC3)C=C2Cl)N=N1)NC4=C(C)N(C)N(C5CCCCC5)C4=O
Molecular Formula
C24H29ClN6O2
Molecular Weight
468.98
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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