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Smurf1-IN-5

CAT: 0931-T211258-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211258-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1824647-09-7
Target
E1/E2/E3 Enzyme
Related Pathways
Ubiquitination
Bioactivity
Smurf1-IN-5 (Compound cpd-6) is an inhibitor of the SMAD ubiquitin regulatory factor (SMURF1) . It reduces the ubiquitination of substrates such as BMPR2 (bone morphogenetic protein receptor 2) and SMAD1, thereby enhancing the BMP (bone morphogenetic protein) signaling pathway. Smurf1-IN-5 holds promise for research in pulmonary arterial hypertension (PAH) .
Smiles
O=C(NC=1C(=O)N(C=2C=CC=CC2F)N(C1C)C)C3=NOC(C=4C=CC(=CC4Cl)C5CC5)=C3C
Molecular Formula
C25H22ClFN4O3
Molecular Weight
480.92
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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