Products for Research Use Only

Smurf1-IN-A01

CAT: 0931-T16904-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T16904-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1007647-73-5
Target
MyD88, Estrogen Receptor/ERR, Others, HSP, NF-κB, Interleukin
Related Pathways
Cytoskeletal Signaling, Others, NF-κB, Metabolism, Endocrinology/Hormones, Immunology/Inflammation
Purity
0.9954
Bioactivity
Smurf1-IN-A01 (A01) is a ubiquitin ligase Smad ubiquitination regulatory factor-1 inhibitor (Kd: 3.664 nM) that enhances BMP-2 responsiveness by preventing Smurf1-mediated Smad1/5 degradation.
Smiles
Cc1ccnn1-c1ccc(cc1)C(=O)N1CCN(CC1)S(=O)(=O)c1ccc(Cl)c(c1)C(F)(F)F
Molecular Formula
C22H20ClF3N4O3S
Molecular Weight
512.93
Shipping Conditions
Ice Packs
Storage Temperature
-20°C