Ac-?IETD-?CHO

• Target:

  Apoptosis

• Related Pathways:

  Apoptosis

• Bioactivity:

  Ac-IETD-CHO is a potent, reversible inhibitor of granzyme B and caspase 8, which also impedes Fas-mediated apoptosis, hemorrhagic conditions, and liver failure. Furthermore, this compound hampers cell death induced by cytotoxic T lymphocytes [1] [2].

• Smiles:

  [C@@H](NC([C@H]([C@H](CC)C)NC(C)=O)=O)(C(N[C@H](C(N[C@@H](CC(O)=O)C=O)=O)[C@@H](C)O)=O)CCC(O)=O

• Molecular Formula:

  C21H34N4O10

• Molecular Weight:

  502.52

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  191338-86-0