Ac-DNLD-CHO

• Target:

  Caspase

• Related Pathways:

  Proteases/Proteasome|||Apoptosis

• Bioactivity:

  Ac-DNLD-CHO (Ac-Asp-Asn-Leu-Asp-CHO) is an inhibitor of Caspase-3/7, with IC50 values of 9.89 nM and 245 nM, and approximate Ki values of 0.68 nM and 55.7 nM, respectively. This compound is utilized in the study of diseases associated with caspase-mediated apoptosis, including neurodegenerative and viral infection diseases [1].

• Smiles:

  [C@H](C(N[C@H](C(N[C@@H](CC(O)=O)C=O)=O)CC(C)C)=O)(NC([C@H](CC(O)=O)NC(C)=O)=O)CC(N)=O

• Molecular Formula:

  C20H31N5O10

• Molecular Weight:

  501.49

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  775289-20-8