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JPS016 TFA

CAT: 0931-T77938-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T77938-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
PROTACs, HDAC
Related Pathways
PROTAC, Chromatin/Epigenetic, DNA Damage/DNA Repair
Bioactivity
JPS016, a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimera (PROTAC), effectively degrades class I histone deacetylase (HDAC), particularly HDAC1/2. This activity is associated with a substantial increase in differentially expressed genes and augmented apoptosis in HCT116 cells [1].
Molecular Formula
C50H64F3N7O10S
Molecular Weight
1012.14
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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