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NH2-methylpropanamide-Exatecan TFA

CAT: 0931-T77889-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T77889-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1817857-35-4
Target
Topoisomerase, ADC Cytotoxin
Related Pathways
DNA Damage/DNA Repair, Antibody-drug Conjugate/ADC Related
Bioactivity
Exatecan TFA, a methylpropanamide-modified derivative of the common ADC cytotoxin Exatecan, serves as a DNA topoisomerase I inhibitor with an IC50 of 2.2 μM (0.975 μg/mL), utilized in the synthesis of ADCs for cancer research [1].
Smiles
C(C(O)=O)(F)(F)F.N(C([C@H](CN)C)=O)[C@@H]1C2=C3C(C=4N(C3)C(=O)C5=C(C4)[C@](CC)(O)C(=O)OC5)=NC=6C2=C(CC1)C(C)=C(F)C6
Molecular Formula
C30H30F4N4O7
Molecular Weight
634.58
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

CatalogName
MBS5819560NH2-methylpropanamide-Exatecan TFA
HY-156686-01NH2-methylpropanamide-Exatecan (TFA)
HY-145397-01(4-NH2) -Exatecan
MBS5800449(4-NH2)-Exatecan
HY-145397S-01(4-NH2) -Exatecan-d5
HY-145397A(R) - (4-NH2) -Exatecan
HY-160885NH2-Gly-PAB-Exatecan-D-glucuronic acid
HY-160885A-01NH2-Gly-PAB-Exatecan-D-glucuronic acid (formic)
GTR19231392-01Mal-PEG8-amide-Val-Ala- (4-NH2) -Exatecan
MBS5819513Mal-PEG8-amide-Val-Ala-(4-NH2)-Exatecan

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