ROS-generating agent 1

• CAS Number :

  2369030-41-9

• Target :

  Reactive Oxygen Species|||Ferroptosis|||Apoptosis|||ROS Kinase|||ROS

• Related Pathways :

  Immunology/Inflammation|||NF-?B|||Tyrosine Kinase/Adaptors|||Apoptosis|||Metabolism

• Purity :

  0.9976

• Bioactivity :

  Ros-generating agent 1 has anticancer activity and generates ROS by covalently modifying Sec-498 residues of TrxR. ROS-generating agent 1 reduces intracellular TrxR protein levels and promotes ROs-dependent apoptosis and ferroptosis in NCI-H460 cells.

• Smiles :

  C(=C\1/C(=O)\C(=C\C2=CC(C(F)(F)F)=CC=C2)\CNC1)\C3=CC(C(F)(F)F)=CC=C3

• Molecular Formula :

  C21H15F6NO

• Molecular Weight :

  411.34

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C