Products for Research Use Only
RegisterLogin

ROS-generating agent 1

CAT: 0013-GTR19219559-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19219559-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
This small molecule induces cancer cell death by covalently targeting the Sec-498 residue of thioredoxin reductase (TrxR), inhibiting its activity and depleting its protein levels. The consequent ROS generation triggers both apoptosis and ferroptosis, as demonstrated in studies using NCI-H460 non-small cell lung cancer cells.
CAS Number
2369030-41-9
Product Name Alternative
Ferroptosis, Apoptosis, ROSgenerating agent 1, ROS-generating agent 1, ROS Kinase, ROSKinase, ROS1
Field of Research
Cell Biology, Immunology & Inflammation, Metabolism Research, Signal Transduction
Purity
99.67% (May vary between batches)
Solubility
DMSO:45 mg/mL (109.4 mM)
Smiles
C (=C\1/C (=O) \C (=C\C2=CC (C (F) (F) F) =CC=C2) \CNC1) \C3=CC (C (F) (F) F) =CC=C3
Molecular Formula
C21H15F6NO
Molecular Weight
411.34
Storage Conditions
-20°C
Notes
For research use only.

Related Products

CatalogName
GTR19213030-01ROS-IN-1
GTR19219595-01ROS inducer 1
GTR19243963-01ROS kinases-IN-1
GTR19188239-01ROS kinases-IN-1
GTR19221404-01ROS-ERS inducer 1
GTR19235262-01Hepatoprotective agent-1
GTR19221409-01Angiogenesis agent 1
GTR19219410-01Therapeutic agent-1
GTR19218305-01Insecticidal agent 1
GTR19206891-01Antifungal agent 1

Alternative Products

CatalogName
BUP05515-01ROS-generating agent 1
C8439-10ROS-generating agent 1
TBI3447-5MGCercosporin, ROS-generating fungal toxin
527840-01ROS
BA6207-10ROS-IN-1
HY-107563ROS 234
MBS344134-01ROS 1
MBS5820548ROS-IN-2
E51A13227ROS Antibody
ENZ-51011ROS-ID®Total ROS detection kit

Popular Products