MMI-0100

• Target:

  MAPK

• Related Pathways:

  MAPK

• Bioactivity:

  MMI-0100, a cell-permeant peptide inhibitor of mitogen-activated protein kinase activated protein kinase II (MK2), effectively reduces intimal hyperplasia ex vivo and in vivo. It specifically suppresses IL-6 expression while not affecting IL-8 expression and mitigates fibrotic processes, including vein graft disease [1].

• Smiles:

  [C@@H] (NC ([C@@H] (NC ([C@@H] (NC ([C@@H] (NC ([C@@H] (NC ([C@@H] (NC ([C@@H] (NC ([C@@H] (NC ([C@@H] (NC ([C@@H] (NC ([C@@H] (NC ([C@@H] (NC ([C@@H] (NC ([C@@H] (NC ([C@@H] (NC ([C@@H] (NC ([C@H] (CC1=CC=C (O) C=C1) N) =O) C) =O) CCCNC (=N) N) =O) C) =O) C) =O) C) =O) CCCNC (=N) N) =O) CCC (N) =O) =O) C) =O) CCCNC (=N) N) =O) C) =O) CCCCN) =O) C) =O) CC (C) C) =O) C) =O) CCCNC (=N) N) =O) (C (N[C@H] (C (NCC (N[C@H] (C (N[C@H] (C (N[C@H] (C (O) =O) C) =O) C) =O) [C@H] (C) C) =O) =O) CC (C) C) =O) CCC (N) =O

• Molecular Formula:

  C98H171N37O26

• Molecular Weight:

  2283.64

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1039342-24-9