MMI-0100

• Target :

  MAPK

• Related Pathways :

  MAPK

• Bioactivity :

  MMI-0100, a cell-permeant peptide inhibitor of mitogen-activated protein kinase activated protein kinase II (MK2), effectively reduces intimal hyperplasia ex vivo and in vivo. It specifically suppresses IL-6 expression while not affecting IL-8 expression and mitigates fibrotic processes, including vein graft disease [1].

• Smiles :

  [C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CC=C(O)C=C1)N)=O)C)=O)CCCNC(=N)N)=O)C)=O)C)=O)C)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)C)=O)CCCNC(=N)N)=O)C)=O)CCCCN)=O)C)=O)CC(C)C)=O)C)=O)CCCNC(=N)N)=O)(C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)C)=O)C)=O)[C@H](C)C)=O)=O)CC(C)C)=O)CCC(N)=O

• Molecular Formula :

  C98H171N37O26

• Molecular Weight :

  2283.64

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1039342-24-9