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Angiopeptin TFA

CAT: 0931-T76042-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T76042-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2478421-60-0
Target
Somatostatin, AChR
Related Pathways
GPCR/G Protein, Neuroscience
Bioactivity
Angiopeptin TFA, a cyclic octapeptide analogue of somatostatin, acts as a partial agonist at sst 2/sst 5 receptors, with IC50 values of 0.26 nM and 6.92 nM, respectively. It effectively inhibits the release of growth hormone and the production of insulin-like growth factor-1 (IGF-1), and either inhibits adenylate cyclase activity or promotes extracellular acidification. Angiopeptin TFA shows promise for use in coronary atherosclerosis research [1] [2].
Smiles
OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CC(C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CS)NC(=O)[C@H](N)Cc1ccc2ccccc2c1)C(=O)N[C@@H](CS)C(=O)N[C@@H]([C@@H](C)O)C(N)=O
Molecular Formula
C58H73F6N11O14S2
Molecular Weight
1326.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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