Angiopeptin TFA

• Target :

  Somatostatin|||AChR

• Related Pathways :

  GPCR/G Protein|||Neuroscience

• Bioactivity :

  Angiopeptin TFA, a cyclic octapeptide analogue of somatostatin, acts as a partial agonist at sst 2/sst 5 receptors, with IC50 values of 0.26?nM and 6.92?nM, respectively. It effectively inhibits the release of growth hormone and the production of insulin-like growth factor-1 (IGF-1), and either inhibits adenylate cyclase activity or promotes extracellular acidification. Angiopeptin TFA shows promise for use in coronary atherosclerosis research [1] [2].

• Smiles :

  OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CC(C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CS)NC(=O)[C@H](N)Cc1ccc2ccccc2c1)C(=O)N[C@@H](CS)C(=O)N[C@@H]([C@@H](C)O)C(N)=O

• Molecular Formula :

  C58H73F6N11O14S2

• Molecular Weight :

  1326.39

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2478421-60-0