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Malantide TFA

CAT: 0931-T75989-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T75989-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
PKA, PKC
Related Pathways
Chromatin/Epigenetic, Cytoskeletal Signaling, Tyrosine Kinase/Adaptors
Bioactivity
Malantide TFA, a synthetic dodecapeptide, originates from the phosphorylation site targeted by cAMP-dependent protein kinase (PKA) on the β-subunit of phosphorylase kinase. Exhibiting a high specificity for PKA with a Michaelis constant (Km) of 15 μM, this compound demonstrates more than 90% inhibition of substrate phosphorylation in the presence of protein inhibitor (PKI) across various rat tissue extracts [1]. Moreover, Malantide TFA acts as an effective substrate for Protein Kinase C (PKC) with a Km of 16 μM [2].
Molecular Formula
C74H125F3N22O23
Molecular Weight
1747.91
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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