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Spadin TFA

CAT: 0931-T75944-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T75944-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
5-HT Receptor, Potassium Channel
Related Pathways
GPCR/G Protein, Neuroscience, Membrane transporter/Ion channel
Bioactivity
Spadin TFA, a natural peptide originating from a propeptide in blood, acts as a powerful TREK-1 channel inhibitor with an IC 50 of 10 nM. It boosts dorsal raphe nucleus 5-HT neurotransmission in mice, activates hippocampal CREB, and promotes neurogenesis. This compound is useful for antidepressant research [1] [2].
Molecular Formula
C92H143F3N26O24
Molecular Weight
2126.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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