Products for Research Use Only

JKC363 TFA

CAT: 0931-T75850-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T75850-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
Melanocortin Receptor
Related Pathways
Neuroscience, GPCR/G Protein
Bioactivity
JKC363 TFA is a selective melanocortin MC4 receptor antagonist that exhibits a 90-fold higher affinity for the MC4 receptor (IC50=0.5 nM) compared to the MC3 receptor (44.9 nM) . This compound effectively inhibits the α-MSH-induced stimulation of TRH release. It also demonstrates an anti-hyperalgesic effect [1] [2].
Molecular Formula
C71H93F3N19O18S2
Molecular Weight
1620.73
Shipping Conditions
Ice Packs
Storage Temperature
-20°C